PARACAIN - Proparacaine 0.5% Ophthalmic Solution

Composition   Proparacaine Hydrochloride U.S.P. 0.5% Chlorbutol (as preservative) I.P 0.5% Aqueous Base q.s. Dosage form Ophthalmic Solution (Eye Drops) Category Topical anesthetic Description Proparacaine hydrochloride ophthalmic solution is a rapidly acting topical anesthetic, with induced anesthesia lasting approximately 10-20 minutes. Indications Proparacaine hydrochloride ophthalmic solution is indicated for procedures in which a topical ophthalmic anesthetic is indicated: corneal anesthesia of short duration, e.g., tonometry, gonioscopy, removal of corneal foreign bodies, and for short corneal and conjunctival procedures. Dosage Removal of foreign bodies and sutures, and for tonometry: 1 to 2 drops (in single instillations) in each eye before operating. Short corneal and conjunctival procedures : 1 drop in each eye every 5 to 10 minutes for 5-7 doses.  Contraindications Proparacaine hydrochloride ophthalmic solution should be considered contraindicated in patients with Known hypersensitivity to any of the ingredients of this preparation. Warnings Prolonged use of a topical ocular anesthetic is not recommended. It may produce permanent corneal opacification with accompanying visual loss. Pregnancy Proparacaine hydrochloride should be administered to a pregnant woman only if clearly needed. Adverse Effects Occasional temporary stinging, burning, and conjunctival redness may occur with the use of proparacaine. A rare, severe, immediate-type, apparently hyperallergic corneal reaction, characterized by acute, intense and diffuse epithelial keratitis, a gray, ground glass appearance, sloughing of large areas of necrotic epithelium, corneal filaments and sometimes, iritis with descemetitis has been reported. Storage Store in a cool dry place. Protect from light. Presentation PARACAIN Eye Drops is available in sterile plastic bottle of 5 ml.