ETAPRED  LS - Loteprednol Etabonate 0.2% Ophthalmic Suspension

Composition   Each ml contains   Loteprednol Etabonate 2 mg Benzalkonium Chloride Solution I.P. 0.02 % V/V Sterile Aqueous Buffered Solution q.s. Dosage form Ophthalmic Suspension Description Etapred  LS (loteprednol etabonate ophthalmic suspension) is a sterile, topical anti-inflammatory corticosteroid for  ophthalmic use. Clinical pharmacology Corticosteroids inhibit the release of inflammatory mediators like prostaglandins Indications and Usage Etapred LS Ophthalmic Suspension is indicated for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis Dosage One drop instilled into the affected eye(s) four times daily. Contraindications Etapred LS (loteprednol etabonate ophthalmic suspension) , as with other ophthalmic corticosteroids, is contraindicated in most viral diseases of the cornea and conjunctiva including epithelial  herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella and also in mycobacterial infection of the eye and fungal diseases of ocular structures. Etapred LS (loteprednol etabonate ophthalmic suspension) is also contraindicated in individuals with known or suspected hypersensitivity to any of the ingredients of this preparation and to other corticosteroids Warnings Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve defects in visual acuity and fields of vision, and in posterior subcapsular cataract formation. Steroids should be used with caution in the presence of glaucoma. Precautions Pregnancy Etapred LS should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing Mothers It is not known whether topical ophthalmic administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Systemic steroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. Caution should be exercised when Etapred  LS (loteprednol etabonate ophthalmic suspension) is administered to a nursing woman. Pediatric Use Safety and effectiveness in pediatric patients have not been established. Storage Store in a cool dry place. Protect from light. Presentation Etapred LS is available in a pack of 5 ml plastic bottle.