DEKORTYN N - Dexamethasone + Neomycin Eye Drops

Composition   Dexamethasone Sodium Phosphate I.P.   Equivalent to Dexamethasone Phosphate 0.1% Neomycin Sulphate I.P.   Equivalent to Neomycin 0.35% Phenyl Mercuric Nitrate I.P. 0.001% (As preservative)   Aqueous Base q.s. Dosage Form Ophthalmic Solution (Eye Drops) Category Antibiotic + Steroid Description Neomycin is a antibiotic used to treat ocular infection by inhibiting the protein synthesis of the bacteria & Dexamethasone is a topical steroid used to treat ocular inflammation by inhibiting the inflammatory mediators. Indications For steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exists. Ocular steroids are indicated in inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe where the inherent risk of steroid use in certain infective conjunctivitides is accepted to obtain a diminution in edema and nflammation. They are also indicated inchronic anterior uveitis and corneal injury from chemical, radiation, or thermal burns, or penetration of foreign bodies. The use of a combination drug with an anti-infective component is indicated where the risk of infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye. The particular anti-infective drug in this product is active against the following common bacterial eye pathogens: Staphylococcus aureus Escherichiacoli Haemophilusinfluenzae Klebsiella/Enterobacter species Neisseria species Dosage Instill one or two drops into the conjunctival sac every hour, when a favorable response is observed, reduce dosage to one drop every four hours. Later, further reduction in dosage to one drop three times daily may suffice to control symptoms. Contraindications Dekortyn -N is contraindicated in patients with known hypersensitivity to any of its components. Precautions Pregnanacy Dekortyn -N should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing Mothers  Systemic absorption of Dekortyn -N may occur when applied topically. Because of the potential for serious, adverse reactions in nursing infants from Dekortyn -N, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Geriatric Use No overall difference in safety or effectiveness have been observed between elderly and younger, adult patients. Adverse Effects The most frequently reported drug related adverse reaction was local burning or discomfort. Storage Store in a cool dark place Presentation Dekortyn -N is available in 5 ml plastic bottle