CHLOROSUN - Chloramphenicol 0.5% Eye Drops

Composition   Chloramphenicol I.P. 0.5% Phenyl Mercuric Nitrate I.P. 0.001% (as preservative)   Aqueous Base q.s. Dosage Form Ophthalmic Solution (Eye Drops) Category Antibiotic Description Chlorosun (chloramphenicol ophthalmic solution) is a topical anti-infective for ophthalmic use. Chloramphenicol is a broad-spectrum antibiotic primarily bacteriostatic and acts by inhibition of protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes. Indications Chlorosun is indicated in the treatment of bacterial conjunctivitis & keratitis. Dosage Instill one or two drops into the affected eye(s) every four hours. In severe infections dosage may be increased to as much as two drops every hour. Contraindications Chlorosun ophthalmic solution is contraindicated in patients with known hypersensitivity to any of its components. Precautions Pregnanacy Chloramphenicol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing Mothers Chloramphenicol appears in human milk following oral administration of the drug. Systemic absorption of chloramphenicol may occur when applied topically. Because of the potential for serious, adverse reactions in nursing infants from chloramphenicol, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Pediatric Use The safety and efficacy in pediatric patients below 1 year of age have not been established. Geriatric Use No overall difference in safety or effectiveness have been observed between elderly and younger, adult patients. Adverse Effects The most frequently reported adverse reactions have been burning, stinging, ocular irritation, and conjunctival hyperemia. Blood dyscrasias, allergic or inflammatory reactions due to individual hypersensitivity, angioneurotic edema, urticaria, vesicular and macula papular dermatitis have also been reported Storage Store in a cool dark place Presentation Chlorosun is available in 5 ml plastic bottle.