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| CIBRIM-Z - Brimondine Tartrate Ophthalmic Solution |
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| Description | ||||||||||||||||||
| Cibrim-Z is an alpha adrenergic receptor agonist. It has a peak ocular hypotensive effect occurring at two hours post-dosing. Pharmacology: Fluoro photometric studies in animals and humans suggest that brimonidine tartrate has a dual mechanism of action by reducing aqueous humor production and increasing uveoscleral outflow. | ||||||||||||||||||
| Indications | ||||||||||||||||||
Cibrim-Z is indicated for lowering intraocular pressure in patients with open angle glaucoma or ocular hypertension. |
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| Dosage | ||||||||||||||||||
| The recommended dose is one drop of Cibrim-Z in the affected eye (s) three times daily, approximately 8 hours apart. If more than one topical ophthalmic product is being used, the products should be administered at least 5 minutes apart. | ||||||||||||||||||
| Contraindications | ||||||||||||||||||
| Cibrim-Z is contraindicated in patients with hypersensitivity to brimonidine tartrate or any component of this medication. It is also contraindicated in patients receiving monoamine oxidase (MAO) inhibitor therapy. | ||||||||||||||||||
| Precautions | ||||||||||||||||||
| Pregnancy: Category C. Cibrim-Z should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the fetus. Lactation: It is not known whether Cibrim-Z is excreted in human milk, although in animal studies, brimonidine tartrate has been shown to be excreted in breast milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Pediatric Use: Brimonidine tartrate ophthalmic solution is not recommended in paediatric patients below the age of 2 years. Geriatric Use: No overall differences in safety or effectiveness have been observed between elderly and other adult patients. |
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| Storage | ||||||||||||||||||
| Store in a cool dry place protect from light. | ||||||||||||||||||
| Presentation | ||||||||||||||||||
| Cibrim-Z is available in a plastic Bottle of 5ml | ||||||||||||||||||