OCCOMOX - Moxifloxacin 0.5% and Dexmethasone 0.1% Eye Drops

Composition w/v   Moxifloxacin Hydrochloride   Equivalent to Moxifloxacin 0.5% w/v  Dexamethasone Sodium phosphate I.P.   Equivalent to Dexamethasone Phosphate 0.1% w/v  Benzalkonium chloride NF 0.01% w/v  (as preservative)   Sterile Aqueous Base q.s. Dosage form Ophthalmic Solution (Eye Drops) Category Antibiotic + Steroid Description OCCUMOX DM is a combination of Moxifloxacin 0.3% and dexmethasone 0.1% . Moxifloxacin is a fourth generation fluoroquinolone controls infection by inhibitting the dna gyrase & topoisomerase iv.Dexamethasone a potent corticosteroid effectively controls the inflammation by inhibiting the release inflammatory mediators. Indications OCCUMOX DM is indicated for steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exists.The combination can also be used for post-operative inflammation and any other ocular inflammation associated with infection. Dosage One or two drops instilled into the conjunctival sac(s), every 4 to 6 hours. During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every two hours.Frequency must be decreased gradually or warranted by improvement in clinical signs. Care should be taken not to discontinue the therapy prematurely.  Contraindications Occumox dm is contraindicated in epithelial herpes simplex keratitis (Dendritic keratitis), vaccinia, varicella, and in many other viral diseases of the conjunctiva and cornea, Mycobacterial infection of the eye and fungal diseases of ocular structures and in individuals hypersensitive to any of the components of the medication. Warning & Precautions Prolonged use of steroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation. Adverse Effects The most frequently reported drug-related undesirable effects seen with moxifloxacin are conjunctival irritation, increased lacrimation, keratitis and papillary conjunctivitis. Secondary Infection: Storage Store in a cool dry place. Protect from light. Presentation OCCUMOX DM eye drops is available in sterile plastic bottle of 5 ml.