|
 |
|
| Composition |
|
| Gatifloxacin I.P. |
|
| Equivalent to Anhydrous Gatifloxacin |
0.3% w/v |
| Prednisolone Acetate USP |
1.0% w/v |
| Benzalkonium Chloride IP |
0.006% w/v |
| (as preservative) |
|
| Sterile Aqueous Vehicle |
q.s |
|
|
| Dosage form |
| Ophthalmic Solution (Eye Drops) |
|
| Category |
| Antibiotic + Steroid |
|
|
|
| Description |
| Gatsun-P is a combination of gatifloxacin a fluoroquinolone antibacterial and prednisolone, a potent corticosteroid. Gatifloxacin results from inhibition of DNA gyrase and Topoisomerase IV. Prednisolone inhibits the inflammatory mediators. |
|
| Indications |
| The combination is used for post-operative inflammation and any other ocular inflammation associated with infection. |
|
| Dosage and Administration |
| One or two drops instilled into the conjunctival sac(s), every 4 to 6 hours or as directed by the physician. |
|
| Contraindiacations |
Gatsun P is contraindicated in epithelial herpes simplex keratitis (Dendritic keratitis), vaccinia, varicella, and in many other viral diseases of the conjunctiva and cornea, Mycobacterial infection of the eye and fungal diseases of ocular structures and in individuals hypersensitive to any of the components of the medication.
Pregnancy
There are no adequate and well-controlled studies in pregnant women; Gatsun-P should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. |
|
| Warnings & Precautions |
| Prolonged use of steroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation. |
|
| Adverse Effects |
| The most frequently reported drug-related undesirable effects seen with Gatifloxacin are conjunctival irritation, increased lacrimation, keratitis and papillary conjunctivitis. |
|
| Storage |
| Store in a cool dry place. Protect from light. |
|
| Presentation |
| GATSUN-P Eye Drops is available in a 5 ml FFS-pack. |
|
